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GHB or Gamma Hydroxybutyrate (C4H8O3) is a central nervous system (CNS) depressant that is commonly referred to as a “club drug” or “date rape” drug. GHB is abused by teens and young adults at bars, parties, clubs and “raves” (all night dance parties), and is often placed in alcoholic beverages. Euphoria, increased sex drive, and tranquility are reported positive effects of GHB abuse.1,2 Negative effects may include sweating, loss of consciousness (reported by 69 percent of users), nausea, hallucinations, amnesia, and coma, among other adverse effects.
Xyrem (sodium oxybate), a brand name prescription drug was approved by the Food and Drug Administration (FDA) in 2002 for the treatment of narcolepsy, a sleep disorder that causes excessive sleepiness and recurring daytime sleep attacks. It is the sodium salt of gamma hydroxybutyrate. Xyrem is a highly regulated drug in the U.S. It is a Schedule III controlled substance, and requires patient enrollment in a restricted access program.
GHB is also a naturally-occurring metabolite of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) found in the brain. The naturally-occurring metabolite GHB is present in much lower concentrations in the brain than those levels found when the drug is abused. As a result of fermentation, natural GHB may also be found in small but insignificant quantities in some beers and wines.
High doses of BUY GHB ONLINE, even without other illicit substances or alcohol, may result in profound sedation, seizures, coma, severe respiratory depression and death. Emergency department episodes related to the use of club drugs usually involve the use of multiple substances, such as marijuana, cocaine, and other club drugs, such as methamphetamine, Ecstasy, or Rohypnol.
γ-Hydroxybutyric acid (GHB), also known as 4-hydroxybutanoic acid, is a naturally occurring neurotransmitter and a psychoactive drug. It is a precursor to GABA, glutamate, and glycine in certain brain areas, and it acts on the GHB receptor and it is a weak agonist at the GABAB receptor.
GHB has been used in a medical setting as a general anesthetic and as a treatment for cataplexy, narcolepsy, and alcoholism.It is also used illegally as an intoxicant, to try to increase athletic performance, and as a date rape drug and as a recreational drug. It is commonly used in the form of a salt, such as sodium γ-hydroxybutyrate (Na.GHB, sodium oxybate, or Xyrem) or potassium γ-hydroxybutyrate (K.GHB, potassium oxybate).
BUY GHB ONLINE is also produced as a result of fermentation, and is found in small quantities in some beers and wines, beef and small citrus fruits.
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4-Hydroxybutansäure – 4-Hydroxybutanoic acid.svg
BUY GHB ONLINE CLINICAL DATA
Synonyms γ-Hydroxybutyric acid
US: C (Risk not ruled out)
administration Usually by mouth; intravenous
N01AX11 (WHO) N07XX04 (WHO)
BUY GHB ONLINE LEGAL STATUS
AU: S8 (Controlled)
CA: Schedule I
DE: Prescription only (Anlage III for higher doses)
NZ: Class B
UK: Class C
US: Schedule I but Schedule III as sodium oxybate
EU: List I (Netherlands)
Bioavailability 25% (oral)
Metabolism 95%, mainly liver, also in blood and tissues
Onset of action Within 5–15 min
Elimination half-life 30–60 minutes
Excretion 5%, kidney
BUY GHB ONLINE IDENTIFIERS
IUPAC name[show] CAS Number
BUY GHB ONLINE CHEMICAL AND PHYSICAL DATA
Molar mass 104.10 g/mol (GHB)
126.09 g/mol (sodium salt)
142.19 g/mol (potassium salt)
3D model (JSmol)
SMILES[show] InChI[show] (verify)